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Search Results for " i factor (complement) "

Targets Recommended: Endogenous Metabolite

1

抑制剂 & 化合物

8

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T80059	Complement factor I	Endogenous Metabolite	Metabolism
	Complement factor I，一丝氨酸蛋白酶，可与辅助因子H (FH)、补体受体1 (CR1/CD35)、C4结合蛋白 (C4BP) 或膜辅助因子蛋白 (MCP/CD46) 结合，调控液相及/或细胞表面补体系统的活性。

化合物

Complement factor I

Cat.No: T80059

Target: Endogenous Metabolite

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01023	Complement factor I Protein, Mouse, Recombinant (His) FIC3b-INA,I factor (...	Mouse	HEK293 Cells
	Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 66.39 kDa and the accession number is Q61129.
TMPH-03273	Complement factor I Protein, Rat, Recombinant (His & Myc) If,Complement factor I,C...	Rat	Baculovirus Insect Cells
	Complement factor I Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 69.2 kDa and the accession number is Q9WUW3.
TMPK-00776	Complement factor I Protein, Human, Recombinant (His) FIC3b-INA,KAF,IF,CFI,	Human	HEK293 Cells
	Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 64.58 kDa and the accession number is P05156.
TMPH-03038	Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO) Cobra venom factor,Complement C3 homolog,C...	Naja kaouthia	E. coli
	Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely re...
TMPK-00570	CD46 Protein, Canine, Recombinant (His) CD46,AHUS2,TRA2.10,LOC609365,TLX,MCP,MIC10,Membrane...	Canine	HEK293 Cells
	CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'. CD46 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells w...
TMPK-00532	CD46 Protein, Cynomolgus, Recombinant (His) CD46,MCP,TLX,MIC10,AHUS2,TRA2.10	Cynomolgus	HEK293 Cells
	CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'. CD46 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cel...
TMPH-02606	CR1L Protein, Mouse, Recombinant (His) Crry,Complement regulatory protein Crry,	Mouse	E. coli
	Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion. CR1L Prot...
TMPJ-00809	CFH Protein, Human, Recombinant (His) CFH,Complement factor H	Human	HEK293 Cells
	Complement Factor H (CFH) is a secreted protein which is a member of the regulators of complement activation family and is a complement control protein. It is expressed by the liver and secreted in plasma. Its principal function is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens or other dangerous material and does not damage host tissue. Factor H regulates complement activation on self cells and surfaces by possessi...

重组蛋白

Complement factor I Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01023

Species: Mouse

Expression System: HEK293 Cells

Complement factor I Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03273

Species: Rat

Expression System: Baculovirus Insect Cells

Complement factor I Protein, Human, Recombinant (His)

Cat.No: TMPK-00776

Species: Human

Expression System: HEK293 Cells

Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO)

Cat.No: TMPH-03038

Species: Naja kaouthia

Expression System: E. coli

CD46 Protein, Canine, Recombinant (His)

Cat.No: TMPK-00570

Species: Canine

Expression System: HEK293 Cells

CD46 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00532

Species: Cynomolgus

Expression System: HEK293 Cells

CR1L Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02606

Species: Mouse

Expression System: E. coli

CFH Protein, Human, Recombinant (His)

Cat.No: TMPJ-00809

Species: Human

Expression System: HEK293 Cells

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